Analytical Method Development and Adaptation
BJL Laboratoires assesses the development and adaptation of specialised analytical methods when existing standard methods cannot directly address a specific industrial or environmental challenge.
When Is Analytical Method Development Needed?
- a new target substance;
- a new sample matrix;
- a quantification limit that does not meet the required sensitivity;
- analytical interferences;
- changes in regulatory requirements;
- internal quality control requirements;
- adaptation of a client's method;
- a new product or process.
Stages of Analytical Method Development
- Assessment of the analytical requirements and expected performance.
- Review of relevant literature and regulatory requirements, where necessary.
- Selection of sample preparation procedures and the analytical technique.
- Feasibility testing.
- Optimisation of analytical conditions.
- Evaluation of method performance.
- Preparation of a protocol or operating procedure.
Method Performance Characteristics That Can Be Evaluated
- selectivity and specificity;
- repeatability;
- reproducibility;
- linearity;
- trueness;
- extraction efficiency or recovery;
- limit of detection (LOD);
- limit of quantification (LOQ);
- robustness;
- measurement uncertainty, where relevant.
Method Development Within BJL's Areas of Expertise
Requests are assessed individually according to the target substance, sample matrix, required technique and expected performance.
BJL Laboratoires works within its areas of expertise in environmental testing, analytical chemistry and microscopy.
Do You Need to Develop an Analytical Method?
Tell us about your sample matrix, target compound, expected concentration range and analytical objective.
Request a Feasibility Assessment